国际娱乐城

Sun Yannan, female, PhD, Lecturer. She graduated from the School of Pharmaceutical Sciences, Peking University in 2019 (majoring in Pharmaceutics). From 2019 to 2021, she conducted postdoctoral research at the School of Pharmaceutical Sciences, Peking University, and joined the Department of Pharmaceutics, School of Pharmaceutical Sciences, Hebei Medical University in 2022. She teaches undergraduate courses such as Biopharmaceutics and Pharmaceutics.

Presides over projects from the National Natural Science Foundation of China (NSFC) Young Scientist Fund (Category C), Hebei Natural Science Foundation Joint Fund for Precision Medicine Innovation Development (Cultivation Program), the Hebei Natural Science Foundation Young Scientist Fund, and the Hebei Higher Education Scientific Research Youth Fund.

Published multiple SCI research articles as the first author in internationally renowned journals such as Bioactive Materials, Nano Letters, Chemical Engineering Journal, and Asian Journal of Pharmaceutical Sciences. Research focuses on: Construction and in vivo applications of smart responsive nanocarriers.

Email: [email protected].

RESEARCH SUPPORT

1. National Natural Science Foundation of China - Young Scientists Fund Project (Category C)，Intracellular and extracellular synergistic modulation of tumor-derived extracellular vesicles by peptide nanoparticles to restore the activity of CD8+ T cells and enhance breast cancer immunotherapy, 2026.1-2028.12, 82504697

2. The Pioneering Project of the Joint Fund for the Development of Precision Medicine of Natural Science Foundation of Hebei Province，Based on the "soft-hard combined" strategy, construct multi-peptide nanoparticles for cascading regulation of CAFs and tumor cells, and use them for enhancing tumor immunotherapy, 2025.1-2027.12, H2025206677

3. Hebei Province Natural Science Foundation Young Scientific Research Project, Peptide-based variable-responsive carriers for immunotherapy combined with tumor treatment, 2022.1-2024.12, H2022206171

4. Youth Fund Project of Higher Education Scientific Research Projects of Hebei Province, Based on the dual regulation strategy, a peptide/siRNA enzyme-responsive self-assembling nanosystem is constructed for enhancing tumor photothermal co-immunotherapy, 2025.1-2027.12, QN2025306

5. Doctoral Startup Fund Project of Hebei Medical University (Spring Rain Program)，Construction and Evaluation of Local Peptide Hydrogel for Cell Membrane Targeted Photodynamic Combined Immunotherapy of Breast Cancer, 2023.1-2024.12, CYQD2023013

RESEARCH PUBLICATIONS

1. Yanan Sun, Bochen Lyu, Chang Yang, Bing He, Hua Zhang, Xueqing Wang*, Qiang Zhang*, Wenbing Dai*, An enzyme-responsive and transformable PD-L1 blocking peptide-photosensitizer conjugate enables efficient photothermal immunotherapy for breast cancer, Bioactive Materials, 2023, 22: 47-59. (IF: 20.3)

2. Yanan Sun, Yumeng Xi, Yuetong Yu, Lu Huang, Yue Li, Yupin Song, Mengyang Liu, Shaokun Yang, Chaoxing He, Wenbing Dai, Hailin Zhang*, Bai Xiang*, Cathepsin B/pH cascade-responsive transformable peptide: Orchestrating endo/lysosomal escape and cytoplasmic release of siRNA to enhance tumor therapy, Chemical Engineering Journal, 2025, 522, 167455. (IF: 13.2)

3. Yanan Sun, Yanqing Liang*, Wenbing Dai, Bing He, Hua Zhang, Xueqing Wang, Jiancheng Wang,Shaohui Huang, Qiang Zhang*, Peptide−Drug Conjugate-Based Nanocombination Actualizes Breast Cancer Treatment by Maytansinoid and Photothermia with the Assistance of Fluorescent and Photoacoustic Images, Nano Letters, 2019, 19(5): 3229-3237. (IF: 9.1)

4. Anpu Yang#, Yanan Sun#, Bochen Lyu#, Binlong Chen, Zhipu Fan, Minghui Li, Yao Zhao, Jijun Fu, Bing He, Hua Zhang, Xueqing Wang, Wenbing Dai*, Qiang Zhang*, One-pot preparation of nanodispersion with readily available components for localized tumor photothermal and photodynamic therapy, Asian Journal of Pharmaceutical Sciences, 2022, 17(1): 120-128. (IF: 11.9)