Dr. Bai Xiang – Professor
发布时间：2021-08-25 浏览次数：0次
Bai Xiang
Professor, Supervisor of Doctorate Candidates, Supervisor of Master's Candidates
Director, Department of Pharmaceutics, School of Pharmaceutical Sciences, Hebei Medical University,
050017, Shijiazhuang, Hebei, CHINA
Tel: 86-311-8626-5591
E-mail: [email protected]
Education
Ph.D. (Pharmaceutics), Peking University (China), 2013
M.S. (Pharmaceutics), Shenyang Pharmaceutical University (China), 2005
Employment
Visiting Professor, St George's University of London, London（2024）
Visiting Professor, University of California, Davis（2019-2020）
Professor, Dept. Pharmaceutics, Hebei Medical University（2018-present）
Research interests
Nanoparticle-based targeted drug/gene delivery System for treatment of various types of tumor and diseases of the nervous system
Representative Publications (//orcid.org/0000-0002-4789-641X)
(1) Sun Y, Xi Y, Yu Y, Huang L, Li Y, Song Y, et al. Cathepsin B/pH cascade-responsive transformable peptide: Orchestrating endo/lysosomal escape and cytoplasmic release of siRNA to enhance tumor therapy. Chemical Engineering Journal. 2025:167455. (Q1, IF= 13.2)
(2) Liu M, Xing R, Chen G, Liang Y, Huang L, Xi Y, et al. Branched ligand-functionalized immuno-evasive PEGylation (BLIP) platform: Breaking through accelerated blood clearance and chemoresistance barriers with dual-targeting RNAi-chemotherapy synergy. Chemical Engineering Journal. 2025:167098. (Q1, IF= 13.2)
(3) Huang L, Guo W, Zhao T, Feng Y, Li Y, An Q, et al. Microfluidic fabrication of lipid nanoparticles for co-delivery of siRNA and hydroxychloroquine: An engineered theranostic platform for enhanced breast cancer treatment. Chemical Engineering Journal. 2025:160172. (Q1, IF= 13.2)
(4) Hao J, Li Y, Huang L, Qi N, Sun Y, He C, et al. Smart Nanoarchitectures for Precision RNA Delivery: Harnessing Endogenous and Exogenous Stimuli in Cancer Treatment. Theranostics. 2025;15(15):7747-78. (Q1, IF= 13.3)
(5) Yang J, Yang S, Cheng W, Wu J, Qu H, Chen H, et al. Self-assembled cyclodextrin-porphyrin nanoplatform for synergistic chemo-phototherapy and targeted delivery of camptothecin against breast cancer. Chinese Chemical Letters. 2025:111901. (Q1, IF= 8.9)
(6) Dang Y, Feng Y, Chen X, He C, Wei S, Liu D, et al. Development of a multi-level pH-responsive lipid nanoplatform for efficient co-delivery of siRNA and small-molecule drugs in tumor treatment. Chinese Chemical Letters. 2024:109660. (Q1, IF= 8.9)
(7) Meng M, Li Y, Wang J, Han X, Wang X, Li H, et al. Innovative nebulization delivery of lipid nanoparticle-encapsulated siRNA: a therapeutic advance for Staphylococcus aureus-induced pneumonia. Journal of Translational Medicine. 2024;22(1):942. (Q1, IF= 7.5)
(8) Zhao T, Ren M, Shi J, Wang H, Bai J, Du W, et al. Engineering the protein corona: Strategies, effects, and future directions in nanoparticle therapeutics. Biomedicine & Pharmacotherapy. 2024;175:116627. (Q1, IF= 7.5)
(9) Xue X, Qu H, Bo R, Zhang D, Zhu Z, Xiang B, et al. A transformable nanoplatform with multiple therapeutic and immunostimulatory properties for treatment of advanced cancers. Biomaterials. 2023;299:122145. (Q1, IF= 15.3)
(10) Zhao T, Liang C, Zhao Y, Xue X, Ma Z, Qi J, et al. Multistage pH-responsive codelivery liposomal platform for synergistic cancer therapy. Journal of nanobiotechnology. 2022;20(1):177. (Q1, IF= 12.6)
(11) Li L, Lindstrom AR, Birkeland AC, Tang M, Lin T-Y, Zhou Y, et al. Deep tumor-penetrating nano-delivery strategy to improve diagnosis and therapy in patient-derived xenograft (PDX) oral cancer model and patient tissue. Nano Research. 2022. (Q1, IF= 10.2)
(12) Ma Z, Lin K, Tang M, Ramachandran M, Qiu R, Li J, et al. A pH-Driven Small-Molecule Nanotransformer Hijacks Lysosomes and Overcomes Autophagy-Induced Resistance in Cancer. Angewandte Chemie (International ed in English). 2022:e202204567. (Q1, IF= 16.8)